Serum Soluble Urokinase Plasminogen Activator Receptor as a Prognostic Biomarker in Children with Chronic Kidney Disease Due to Congenital Anomalies of the Kidney and Urinary System
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: This study aimed to evaluate the relationship between serum soluble urokinase plasminogen activator receptor (suPAR) levels and chronic kidney disease (CKD) stages in children with CAKUT, the leading cause of pediatric CKD. Metarials and Methods: Forty-two children with CAKUT-related CKD and 42 healthy controls were prospectively enrolled. Serum suPAR levels, estimated glomerular filtration rate (eGFR), and other laboratory parameters were compared. ROC analysis was used to assess the diagnostic performance of suPAR. Results: suPAR levels were significantly higher in the patient group (p
Authors: Aylin Gençler, Seyhan Taşkın
Institutions: Eskişehir City Hospital, Harran University
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415056121