Work

An exceedingly rare case of de novo hepatic angiosarcoma in a transplanted liver

Year: 2025

Type: article

Abstract: De novo primary hepatic angiosarcoma is an exceedingly rare malignancy in transplanted livers. Only 1 previous case has been reported in the literature. The diagnosis is usually challenging due to non-specific clinical presentation and overlapping imaging findings with other conditions. These rapidly progressing, multifocal lesions have previously been described to have varied growth patterns but are typically hypo-enhancing on gadoxetate disodium (Primovist) enhanced MRI. Surgical resection and adjuvant chemotherapy are potential options of treatment for hepatic angiosarcomas. Despite this, prognosis of patients at diagnosis is extremely poor. In this report we present imaging findings of a liver transplant recipient despite biopsy-confirmed hepatic angiosarcoma, and discuss the diagnostic complexities involved.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.09.025

Authors: Howard Chow, Samer Ghattas, Joshua Liu, David Bowen

Institution: Royal Prince Alfred Hospital

Language: English

Topic: Vascular Tumors and Angiosarcomas

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600