Evaluation of the Application Value of Optogenetics Technology in the Development of Immunotherapy Methods for Tumors
Year: 2025
Type: article
Abstract: In the field of tumor treatment, traditional methods have limitations, and tumor immunotherapy has become an important direction. As a cutting-edge discipline, optogenetics has been widely explored for application in tumor immunotherapy, such as regulating the activity of immune cells and influencing the tumor-related nervous system. However, there are still deficiencies in the application of this technology in tumor immunotherapy, such as the specific expression of photosensitive proteins and the precise delivery of light in vivo, which have not yet been resolved. This focuses the core mechanisms of optogenetic technology, elaborates in detail on its applications and research progress in regulating tumor immune cells such as T cells and macrophages, as well as improving the tumor microenvironment, and explores the prospects of its combined application with other tumor treatment technologies. The results indicate that optogenetic technology holds great potential in the development of tumor immunotherapy methods. The prospects. The results show that optogenetic technology has great potential in the development of tumor immunotherapy methods. This study provides new theoretical and practical references for tumor immunotherapy. In the future, technical challenges need to be further overcome. Subsequent research can focus on optimizing the expression of photosensitive proteins and the light delivery system, etc., to promote the application and development of optogenetic technology in tumor immunotherapy.
DOI: 10.62051/e15j8a18
Author: Huishan Chen
Institution: Ocean University of China
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415075820