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NARESMA in a pediatric patient: Early cytological detection to prevent CRSwNP progression

Year: 2025

Type: article

Abstract: A 13-year-old girl presented with persistent nasal obstruction and rhinorrhea unresponsive to standard antihistamines. Nasal cytology revealed abundant eosinophils and degranulated mast cells, consistent with NARESMA—a mixed non-allergic rhinitis subtype. A CT scan showed lobulated, pseudopolypoid mucosal thickening in both maxillary sinuses, suggestive of early mucosal remodeling. Given the established link between NARESMA and CRSwNP, early identification prompted preventive topical corticosteroid treatment. This case highlights the importance of nasal cytology in pediatric patients to identify type 2 inflammation early and prevent progression to more severe disease.

Source: Otolaryngology Case Reports

DOI: 10.1016/j.xocr.2025.100707

Authors: Matteo Gelardi, Rossana Giancaspro, Michele Cassano

Institution: University of Foggia

Language: English

Topic: Sinusitis and nasal conditions

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,110