Year: 2025
Type: article
Abstract: Objective: Insomnia (ID) is the most common clinical disorder afflicting people of all ages, races, and social classes. This study was to explore changes in the brain's nervous system of insomnia patients after TMS treatment and construct a prognostic prediction model. Method: This study involved collecting EEG data of 15 patients before and after treatment, extracting features (approximate entropy, sample entropy, alignment entropy, power spectral density, median, mean, kurtosis, and skewness), and building an SVR model. Results: -test showed significant differences in PSQI and ISI total scores before and after TMS treatment, indicating its therapeutic effect. Correlation coefficients between 40 indicators and scale differences were calculated, and significant characteristic values were further analyzed. SVR models for predicting ISI and PSQI scale pre-post differences were constructed. Both had predictive ability. Conclusion: This work proposes the first SVR model leveraging pre-treatment EEG features to predict TMS therapeutic outcomes for insomnia. TMS treatment can change brain waves, and the model is expected to be applied clinically, though with limitations such as small sample size and insufficiently detailed brain region division.
Source: Frontiers in Neuroscience
Authors: Jiaxiu He, Jin-xiang Cheng, Changjun Su, Jun Zhang
Institution: Tang Du Hospital
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4415097756