Work

Discovery of a 1 H -Pyrazol-3-Amine Derivative as a Novel, Selective, and Orally Available RIPK1 Inhibitor for the Treatment of Inflammatory Disease

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02124

Authors: Qiangqiang Tao, Xixiang Li, Hongwei Yu, Fengming Zou, Juan Liu, Juan Liu, Qingwang Liu, Qingwang Liu, Aoli Wang, Chen Hu, Li Wang, Wenchao Wang, Beilei Wang, Qingsong Liu, Qingsong Liu, Jing Liu, Jing Liu

Institutions: University of Science and Technology of China, Chinese Academy of Sciences, Hefei Institutes of Physical Science

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui Provincial Key Research and Development Plan, Major Science and Technology Projects in Anhui Province

Awards: G1802372243, G2926024344, G4022729862, G4690051989, G6768295759

OpenAlex ID: W4415101744

FWCI: 1.26

Cites: 41

Cited by: 5

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