Work

Thoughts on the application of sirolimus

Year: 2025

Type: article

Abstract: that sirolimus may inhibit the growth of K562 cells via the SHP1/STAT3 pathway.However, due to differences in both the drugs and cell lines used, further experiments are needed to verify whether sirolimus acts through the SHP1/ STAT3 pathway in leukemia cell lines other than HEL (including K562).We are extremely grateful for the opportunity to share our views and would be happy to engage in academic exchanges.We are also very grateful to the authors for providing us with research ideas through their experimental results.

Source: Annals of Hematology

DOI: 10.1007/s00277-025-06660-z

Authors: Ying Liu, Yanna Zhao

Institutions: Zhejiang Chinese Medical University, Zhejiang Provincial Hospital of TCM

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,590