Work

Nodular Lymphoid Hyperplasia of the Gastrointestinal Tract with Selective IgA Deficiency in an Adult Patient: A Case Report

Year: 2025

Type: article

Abstract: Nodular lymphoid hyperplasia of the gastrointestinal tract is a rare and benign condition which may accompany immunodeficiency. Although being benign, it carries risk for intestinal and extraintestinal lymphoma. There is no specific and definitive treatment for NLH. Thus, treatment is dependent on the management of the associated conditions. Duodenal and terminal ileal biopsies from a 54-year-old woman with multiple mesenteric lymphadenopathy and gastrointestinal lymphoid hyperplasia revealed nodular lymphoid hyperplasia as well as a paucity of plasma cells. Based on histopathological findings and laboratory results, a diagnosis of selective IgA deficiency was made. It is important to evaluate patients with nodular lymphoid hyperplasia for additional histopathological findings due to the association with possible immune deficiency such as absence or scarcity of plasma cells.

Source: Hitit Medical Journal

DOI: 10.52827/hititmedj.1567949

Authors: Arzu Hazal Aydın, Mustafa Ergin, Seda Tas Ayçiçek

Institution: Aksaray University

Language: English

Topic: Immunodeficiency and Autoimmune Disorders

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: American Heart Association