Work

Management of Chronic Hyponatremia in the Outpatient Setting

Year: 2025

Type: article

Abstract: The diagnostic evaluation and management of chronic hyponatremia in outpatients can be challenging for several reasons. First, chronic hyponatremia is often mild, leading to uncertainty about whether it is clinically significant and warrants further diagnostic evaluation and treatment. Second, if the initial diagnostic workup does not identify a clear cause, it becomes uncertain how much further investigation is required. Third, when no clear cause is found or the underlying condition cannot be treated, physicians may struggle to choose the most appropriate treatment approach. This review offers practical guidance to navigate these challenges in managing chronic hyponatremia in the outpatient setting.

Source: American Journal of Kidney Diseases

DOI: 10.1053/j.ajkd.2025.06.024

Authors: Angelique B.M.C. Savelberg, Ewout J. Hoorn, Julie C. Refardt

Institutions: Erasmus MC, Erasmus University Rotterdam

Language: English

Topic: Electrolyte and hormonal disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,900