Efficacy of preanesthetic assessment combined with pain neuroscience education in reducing anxiety, stress, and pain in elective hysterectomy: A randomized controlled trial protocol
Year: 2025
Type: article
Study design: Study Protocol
Abstract: Introduction: Elective abdominal hysterectomy is often accompanied by high preoperative anxiety and stress, which can exacerbate postoperative pain. Objectives: To determine whether the addition of pain neuroscience education to standard preanesthetic evaluation reduces preoperative anxiety and perceived stress and decreases postoperative pain among women undergoing elective total abdominal hysterectomy. Methods: This single-center randomized controlled trial will enroll 62 adult female patients. Participants will be randomly assigned, in a 1:1 ratio, to the intervention group-standard preanesthetic assessment and pain neuroscience education-or the control group-standard preanesthetic assessment alone. Primary outcomes (pain on the Visual Analog Scale [VAS], anxiety on the Beck Anxiety Inventory [BAI],, and total score on the Perceived Stress Scale [PSS]) will be assessed at three time points: preoperatively, 1 hour postoperatively, and 8 hours postoperatively. Secondary outcomes will include the Quality of Recovery-15 (QoR-15) score and the requirement for rescue analgesia. Expected results: We anticipate that integrating pain neuroscience education with standard preanesthetic evaluation will reduce anxiety and stress, decrease postoperative pain intensity, and improve overall recovery in women undergoing elective hysterectomy. Registration: ClinicalTrials.gov Identifier: NCT05435508.
Source: Medwave
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $600
OpenAlex ID: W4415122905
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