Work

Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity

Year: 2025

Type: article

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/2rjr-tp20

Authors: Hwang, Duhyeong, Dismuke, Taylor, Kagel, John R, Zamboni, William, Kabanov, Alexander V, Ramsey, Jacob D, Lim, Chaemin, Gershon, Timothy R, Sokolsky-Papkov PhD, Marina, Tikunov, Andrey, Rosen, Elias P

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: St. Baldrick's Foundation, Directorate for Engineering, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke

OpenAlex ID: W4415139232

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