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Can Symptoms Predict Delayed Gastric Emptying in Diabetic Patients: A Multicenter Study to Revisit Gastroparesis

Year: 2025

Type: article

Abstract: Background/Aims: This study aims to assess whether specific symptoms from the Gastroparesis Cardinal Symptom Index (GCSI) could predict delayed gastric emptying and to establish the prevalence of gastroparesis (GP). Methods: > 85 minutes and/or gastric retention > 8% at 3 hours. Results: = 0.028) in multivariate analysis. The area under the receiver operating characteristic curve for the GCSI in predicting GP was 0.672, with an optimal cutoff value of 1.78 (sensitivity 79.31%, specificity 49.54%). The prevalence of GP, defined by both GCSI ≥ 1.78 and abnormal GES, was 16.67% among diabetic patients. Notably, 16 (11.59%) patients had rapid emptying. Conclusion: Diabetic patients exhibiting specific cardinal symptoms should be considered for GES evaluation, as the overall GCSI score independently predicts delayed gastric emptying. This study suggests that the GCSI may be useful as a screening tool rather than a diagnostic method for diabetic gastroparesis.

Source: Journal of Neurogastroenterology and Motility

DOI: 10.5056/jnm25027

Authors: Chen-Shuan Chung, Jui-Sheng Hung, Ming-Hung Hsu, Ning-Hsuan Chin, Ming-Wun Wong, Wei-Yi Lei, Tzong-His Lee, Hua-Fen Chen, Yen-Wen Wu, Jiann-Ming Wu, Kuo-Hsin Chen, Wen-Lun Wang, Chien-Lin Chen

Institutions: Far Eastern Memorial Hospital, Yuan Ze University, Tzu Chi Foundation, E-Da Hospital, I-Shou University, National Yang Ming Chiao Tung University

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415147273

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