Work

A non-canonical aryl hydrocarbon receptor pathway authorizes and safeguards clinical-scale expansion of functional human endothelial cells

Year: 2025

Type: article

Source: Nature Cardiovascular Research

DOI: 10.1038/s44161-025-00716-z

Authors: Yang Lin, Fuqiang Geng, Jae-Hung Shieh, Lisa K. Torres, Musia Sominskaia, Meng Gao, Matthew Wingo, Kevin Chen, Samir Rustam, Raul Chavez, Renat Shaykhiev, Aleksandra Kopacz, Bradley Pearson, David Redmond, Ryan Schreiner, Shahin Rafii

Institutions: Cornell University, Weill Cornell Medicine, NewYork–Presbyterian Hospital

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, American Heart Association, New York State Stem Cell Science, National Institutes of Health, Weill Cornell Medical College, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Specialized Endothelium Polarizes Macrophages for Adipogenic Dependent Cardiovascular Function, G1566140461, Niche signals in HSC genesis, G3420401719, ABCG2+ Endothelial Stem and Progenitor Cells for Regeneration of Vascularized Tissues, G7251163372, G8880025940, Endothelial cell transplantation for multi-organ repair to counter radiation injury, Human iPSC intestine mimetics with integrated mesenchymal, endothelial and enteric nervous tissue, Adaptable tissue-specific endothelial cells for organ regeneration, Derivation of pancreatic islet-like organoids from human gastric stem cells, Molecular Determinants of liver sinusoidal endothelial cells for hepatic regeneration

OpenAlex ID: W4415156059

FWCI: 0.597

Cites: 50

Cited by: 2

Related to: 10