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When interstitial lung diseases associates pulmonary hypertension, what to do?

Year: 2025

Type: article

Abstract: Pulmonary hypertension (PH) is one of the major comorbidities of interstitial lung diseases (ILD) and negatively impacts on patients' symptoms and prognosis.PH-ILD diagnosis is made following a three-step strategy.In a first step, suspicion of PH-ILD should be raised if a combination of symptoms, signs, functional impairments, radiological features, and biomarkers is present.In a second step, patients in whom PH-ILD is suspected should undergo transthoracic echocardiography (TTE) for PH screening.In a third step, depending on TTE findings and clinical suspicion, right heart catheterization should be performed to diagnose or rule out PH. Once PH-ILD is diagnosed, a holistic approach is needed, considering optimization of the underlying ILD, assessment of comorbidities, pulmonary rehabilitation, oxygen supplementation, symptom control, evaluation for lung transplantation, and PH therapy.The decision about PH-targeted therapies should be made using a multimodal approach in a multidisciplinary PH-ILD committee.

Source: Barcelona Respiratory Network

DOI: 10.23866/brnrev:2025-m0136

Authors: David Rodríguez-Plaza, Jesús Ribas, Maria Molina-Molina

Institutions: Bellvitge University Hospital, Institut d'Investigació Biomédica de Bellvitge

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415175069