Histopathology and Cytology Laboratory: The Cornerstone of Accurate Diagnosis in Modern Medical Practice
Year: 2025
Type: article
Abstract: Background: Histopathology and cytology are pivotal diagnostic disciplines that utilize microscopic analysis of tissues and cells to detect diseases, including cancers and inflammatory conditions. Aim: This article aims to provide a comprehensive overview of the techniques, processes, and quality control measures employed in histopathology and cytology laboratories. Methods: A detailed review of histopathological and cytological procedures, including specimen preparation, fixation, processing, processing embedding, sectioning, staining, and quality assurance protocols, was conducted based on established guidelines and literature. Results: The study outlines key techniques such as routine histopathology, frozen section analysis, immunohistochemistry, special staining, and cytology, emphasizing their role in accurate diagnosis. Fixation with 10% neutral buffered formalin, tissue processing with automated systems, and precise sectioning (3–5 μm) ensure high-quality slides. Quality control measures, including proper labeling and standardized protocols, minimize errors. Conclusion: Histopathology and cytology laboratories are essential for precise disease diagnosis, leveraging advanced techniques and rigorous quality control to enhance patient outcomes.
DOI: 10.64483/jmph-118
Authors: Amnah Ahmed omer Al-Khateeb, Shamaa Qassem Asseri, Noha khalid Nooh, Ala Hleel Alharbi, Suzan Shafeeq Alkhateeb, Jehan Abdulmajeed Alwahidi, Raneem Rashad Ashour, Kolod Abdulaziz Bokari, Khaled Ibrahim Alghamdi, Hatim Abdullah Alshahri
Institutions: Ministry of Health, Al-Thagher General Hospital
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4415183642
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