Socioeconomic Disparities in Patients Undergoing Alcohol Septal Ablation for Hypertrophic Cardiomyopathy
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Alcohol septal ablation (ASA) effectively treats select patients with hypertrophic obstructive cardiomyopathy (HOCM).Our study analyzes socioeconomic and geographic factors' influence on post-ASA outcomes to improve patient care and accessibility. Methods: Using the National Inpatient Sample (2016-2021) and International Classification of Diseases 10thRevision codes, we identified patients with a primary diagnosis of HOCM who underwent ASA.Study populations were categorized into 3 groups based on the poverty income ratio.The primary outcome was in-hospital complications following the procedure.Secondary outcomes included length of stay, hospitalization costs, and disposition status.Results: Of 8585 patients who underwent ASA, 45.3% were from low SES backgrounds.Medicare was the primary payer, with treatments predominantly occurring in urban teaching hospitals for elective procedures in the southern region.Low and middle-SES patients showed higher rates of in-hospital mortality, sudden cardiac arrest, and increased pacemaker placements compared to high-SES groups.They experienced more extended hospital stays, which was associated with higher hospitalization costs and more transfers to skilled nursing facilities than high SES patients (all P < .05).However, other complications, such as acute stroke and acute kidney injury, showed no significant differences among the groups.Conclusions: Lower and middle socioeconomic HOCM patients who underwent ASA face higher in-hospital mortality, more sudden cardiac arrests, increased pacemaker placements, and more extended hospital stays compared to higher socioeconomic patients, highlighting the need for standardized outcomes for all ASA patients.
Institutions: The University of Texas at San Antonio Health Science Center, The Wright Center for Graduate Medical Education, New York Medical College, Saint Michael's Medical Center, Unity Health System, University of California, Los Angeles, The Lundquist Institute, Dow University of Health Sciences, Wayne State University, Detroit Medical Center
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,400
OpenAlex ID: W4415200184
