Work

Off-label Use of Gastrointestinal Multiplex PCR Panel for the Diagnosis of Amoebic Liver Abscess: A Three-case Pediatric Report

Year: 2025

Type: article

Abstract: Diagnosis of amoebic liver abscess is challenging. A multiplex polymerase chain reaction panel, traditionally employed for the detection of enteric pathogens in stool, proved useful for the rapid diagnosis in 3 pediatric patients when used off-label on liver abscess fluid. While this approach enabled timely and targeted antiamoebic therapy, highlighting its potential in high-burden, resource-limited settings, it represents an unvalidated use of the technology that requires further investigation.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofaf631

Authors: Michael Muñoz-Rosa, Natalia Arango-Serna, Juan Mesa-Monsalve, Alejandro Diaz-Diaz

Institutions: Universidad CES, Corporación Universitaria Remington, Hospital Pablo Tobon Uribe

Language: English

Topic: Amoebic Infections and Treatments

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053