Work

Another Consequence of Overturning Roe: Imperiling Progress on Clinical Research in Pregnancy

Year: 2025

Type: article

Abstract: In recent years, tremendous progress has been made toward recognizing the need for improved medical knowledge for pregnant people, a population group that has long been excluded from clinical trials and suffered the harms that result from a poor evidence base to inform care (Lyerly, Little, and Faden 2008). From the National Institutes of Health (NIH) to the Food and Drug Administration (FDA), federal agencies have signaled strong support for closing knowledge gaps in pregnancy, in part through advancing responsible inclusion of pregnant individuals in clinical research (e.g., FDA 2018; PRGLAC 2018). As evidence of progress, a new National Academies report on improving representation in clinical trials emphasizes that a more equitable research enterprise would be responsive to the clinical needs of pregnant people (NASEM 2022).

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/d7pa-pk68

Authors: Waggoner, Miranda R., Lyerly, Anne Drapkin

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Ethics in Clinical Research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: green

Funders: Greenwall Foundation, Directorate for Social, Behavioral and Economic Sciences, National Institute of Allergy and Infectious Diseases