Work

Effect of isofetamid on SDHI-resistant isolates of Botrytis cinerea

Year: 2025
Type: article
Abstract: Tests of sensitivity to isofetamid conducted with Botrytis cinerea isolated from Hokkaido (2011-2016) and other districts in Japan (2017-2018) revealed the absence of isolates with reduced sensitivity.Isolates of B. cinerea with mutation H272Y/R in sdhB, collected in Germany and Japan, resulted in high and moderate resistance to boscalid and many other succinate dehydrogenase inhibitors (SDHIs), respectively.However, these isolates were as sensitive as wild-type isolate to isofetamid.In contrast, isolate BC-50 [P225F] and BC-49 [H272L] caused moderate to high resistance to isofetamid.Considerable differences in mycelial growth, conidiation, conidial germination, and pathogenicity were not observed between these resistant isolates and sensitive isolates.A competitive assay between resistant isolate BC-50 [P225F] and BC-49 [H272L] and B05.10 [wild type], however, revealed the disappearance of resistant isolates after several generations of mixed incubation in in vitro and in vivo conditions.
Language: English
Open Access status: diamond
OpenAlex ID: W4415202438
FWCI: 0.958
Cites: 17
Cited by: 1
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