Work

Laparoscopic management of multiple retroperitoneal ganglioneuromas with 5-year follow-up: a case report

Year: 2025

Type: article

Abstract: BACKGROUND: Ganglioneuromas are the rarest and most benign of the neuroblastic tumors. Although generally benign, multiple retroperitoneal ganglioneuromas have been documented. However, only one case in previous studies underwent complete resection of all retroperitoneal lesions while the follow-up time was relatively short. CASE PRESENTATION: Here, we presented two female patients in their twenties who were diagnosed as multiple retroperitoneal ganglioneuromas by percutaneous biopsy, with tumor involvement in adrenal, retroperitoneal and pelvic regions. Complete excision of all detectable lesions was performed by laparoscopic dissection. Both patients had a good postoperative recovery and remained recurrence-free at the 5-year follow-up. CONCLUSIONS: To our knowledge, the present study firstly reported cases of multiple retroperitoneal ganglioneuromas with a 5-year follow-up, indicating the safety and efficacy of laparoscopic dissection of multiple retroperitoneal ganglioneuromas.

Source: BMC Urology

DOI: 10.1186/s12894-025-01952-y

Authors: Mengchao Wei, Houfeng Huang, Yu Xiao, Xinrong Fan

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital

Language: English

Topic: Neuroblastoma Research and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990