Work

Case report: Adolescent breast hypertrophy with a tendency toward phyllodes tumor formation: first reported case in China

Year: 2025

Type: article

Abstract: Adolescent breast hypertrophy is a rare and persistent condition that affects peripubertal females both physiologically and psychologically. We present a case of a 14-year-old patient with bilateral giant breast enlargement who underwent a successful reduction mammoplasty of 16.5% Body Weight. The right breast exhibited focal interstitial proliferation myofibroblasts, suggesting a potential risk for phyllodes tumor development. This finding represents a novel histopathological association, unreported in the literature and first documented in China.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1652446

Authors: Ruiheng Liao, Yang Xiao, Yujing Chang, Zhang Zhang, Yange Zhang

Institution: West China Hospital of Sichuan University

Language: English

Topic: Breast Lesions and Carcinomas

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801