Work

A case of primary pseudohypoaldosteronism accompanied by respiratory distress syndrome

Year: 2025

Type: article

Abstract: There is reported a case of a 5-month-old boy diagnosed with Type I pseudohypoaldosteronism which is a rare salt-losing disease caused by resistance of the target organs to aldosterone. Diagnosis was based on clinical presentation with frequent admissions from a young age due recurrent episodes of vomiting and wheezing as well as relevant electrolyte disturbances. It is interesting that during hospitalizations, the baby showed recurrent episodes of wheezing not responding to b-agonists and corticosteroids and depended on daily oxygen supplementation. Molecular investigation of the ENac gene was normal. The systemic form of type I pseudoaldosteronism involves pulmonary dysfunction in addition to increased levels of aldosterone.

Source: Endocrine and Metabolic Science

DOI: 10.1016/j.endmts.2025.100276

Authors: Aikaterini Salavoura, Christina Kanaka, Evaggelia Lykopoulou, Despina Lazopoulou

Institutions: National and Kapodistrian University of Athens, Children's Hospital Agia Sophia

Language: English

Topic: Hormonal Regulation and Hypertension

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,910