Work

Reactive granulomatous dermatitis arising in the setting of interleukin-17 inhibition successfully treated with tofacitinib

Year: 2025

Type: article

Abstract: Reactive granulomatous dermatitis (RGD) encompasses a spectrum of cutaneous granulomatous disorders. Classically, these eruptions had been divided into interstitial granulomatous dermatitis, interstitial granulomatous drug reaction, and palisaded neutrophilic and granulomatous dermatitis. However, more recently RGD, which encompasses these three diagnoses which may overlap with one another, has become the preferred nomenclature. RGD is most commonly associated with inflammatory arthritis and systemic lupus erythematosus, as well as the use of certain medications, including tumor necrosis factor inhibitors.

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2025.09.043

Authors: Sarah L. Spaulding, A. Mitchel Wride, Michael J. Murphy, Muhammad H. Junejo, William Damsky

Institution: Yale University

Language: English

Topic: Autoimmune and Inflammatory Disorders

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $750