Work

Na2SeO3 Exposure Inhibits Locomotion and Reproduction via Oxidative Stress Mechanism in Bioindicators C. elegans and Acrobeloides sp.

Year: 2025

Type: article

Abstract: Selenium (Se) fertilizers are widely used in Se biofortification. However, excessive application of Se fertilizers can easily cause soil Se accumulation and threaten soil organisms, so it is necessary to carry out research on the effects of Se on single species, especially on indigenous organisms in soil. In this study, as significant bioindicators, Caenorhabditis elegans and Acrobeloides sp. were used as research subjects to explore the effects of short-term Se exposure on the total Se content, Se speciation, and physiological and biochemical functions in nematodes. The results showed that total Se content in both nematodes increased significantly with higher Se exposure concentrations, and Se mainly exists in the speciation of selenomethionine (SeMet) and selenocysteine (SeCys2). Exposed to high concentrations of Na2SeO3 (≥3 mg/kg), Caenorhabditis elegans and Acrobeloides sp. were strikingly inhibited in their locomotion and reproduction, and oxidative stress response was induced, which showed a significant increase in ROS, MDA, and SOD. Pearson correlations suggested a depressant effect on nematodes by oxidative stress mechanism. This study provides an important basis for the soil ecotoxicity assessment of Se and highlights the unique value of Acrobeloides sp. in ecotoxicological studies.

Source: Toxics

DOI: 10.3390/toxics13100870

Authors: Fan Jin, Jiaping Song, Shanshan Niu, Xuebin Yin

Institutions: Anhui University of Science and Technology, Anhui Science and Technology University, University of Science and Technology of China

Language: English

Topic: Environmental Toxicology and Ecotoxicology

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDGs: Zero hunger, Life on land

Open Access status: gold

Estimated APC paid: $3,137