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Yeast genomes show how large genomic variations affect trait diversity

Year: 2025

Type: article

Abstract: Almost-complete genomes of more than 1,000 strains of the single-celled yeast species Saccharomyces cerevisiae have been assembled and integrated with phenotypic (trait) measures of growth and of RNA and protein expression. The analysis shows how large genomic variations called structural variants disproportionately shape traits. Structural variants have a disproportionately large effect on traits such as growth and gene expression.

Source: Nature

DOI: 10.1038/d41586-025-03327-7

Language: English

Topic: Fungal and yeast genetics research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $12,690

OpenAlex ID: W4415231503

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Cites: 5

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