The clinical value of fibrinogen and thromboelastography in the predictive assessment of the progression of persistent postpartum hemorrhage
Year: 2025
Type: article
Study design: Observational Study
Abstract: This study aims to explore the value of fibrinogen (FIB) and thromboelastography in evaluating persistent postpartum hemorrhage. A total of 130 parturients were divided into the control group (non-persistent postpartum hemorrhage, n=83) and the observation group (persistent postpartum hemorrhage, n=47), and the observation group was further divided into the mild bleeding group (n=30) and the severe bleeding group (n=17). FIB and D-dimer (D-D) were measured by an automatic coagulation analyzer, and the coagulation reaction time and coagulation time were measured by thromboelastography. FIB was decreased, while D-D levels, R value, and K value were increased in the observation group and the severe bleeding group (p<0.05). FIB was negatively correlated with the R and K values (r=-0.957, -0.921), while D-D was positively correlated with them (r=0.943, 0.968). Receiver operating characteristic curve analysis showed that the areas under the curve of FIB, D-D, R value, and K value were 0.861, 0.892, 0.943, and 0.976, respectively (p<0.05). FIB and thromboelastography parameters are related to the severity of persistent postpartum hemorrhage.
Source: Italian Journal of Medicine
Authors: Huicong Yin, Huili Fan, Wenjuan Ma
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415239765