Year: 2025
Type: article
Abstract: In this issue of Blood, Guo et al 1 describe a novel mechanism of NOTCH1 pathway activation, involving the most frequent 3' untranslated region (UTR) mutation (g.139390152, A>G), corresponding to a A>G mutation occurring 371 nucleotides downstream of the 7668 nucleotide-long NOTCH1 coding sequence.
Source: Blood
Authors: Federico Pozzo, Valter Gattei
Institution: Centro di Riferimento Oncologico
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4415249284