Intensive, Multi-Technology Rehabilitation programme for Chronic Stroke Survivors: A Phase I single-arm repeated-measures study (Preprint)
Year: 2025
Type: preprint
Study design: Clinical Trial
Abstract: BACKGROUND The need to meet minimum guideline recommendations for rehabilitation after stroke motivated the cocreation of a multi-technology enriched rehabilitation gym (TERG). Previous research has established the feasibility and acceptability of this approach in chronic and sub-acute stroke populations. OBJECTIVE This study aimed to gather preliminary evidence, and effect sizes, on the effectiveness of a multi-technology intervention for motor recovery in a chronic stroke population and identify factors that explain variation in response. METHODS This was a Pre-Post, single arm study design located in a rehabilitation research centre. Participants had a diagnosis of stroke, at least 12 months previously, with consequent motor disability. Following baseline measures, an 8-week exercise program using the TERG (e.g., virtual reality treadmills, power-assisted equipment, balance trainers, and upper limb training systems) was individually tailored by a physiotherapist in partnership with participants. Standard measures of activity and participation were recorded two weeks before (baseline), immediately before and immediately post (outcome) intervention. RESULTS Sixty-seven individuals participated, mean age 60.49 (SD 14.44) years, 41.87 (41.31) months since stroke, 51 were male, 26 had aphasia, mean MoCa score of 25.56 (6 to 30). Eight individuals (11.94%) did not complete the programme (transport difficulties n=5, illness n=1, unknown n=2), five withdrawing before baseline. The remaining 59 participants (88.06%) completed an average of 18.12 (SD 6.49,10-38) two-hour sessions. There were statistically significant (p <.05) improvements from baseline to outcome on every variable, with varying effect sizes. Cluster analysis distinguished two sub-groups. Group 1 (n = 20) had poorer balance, arm function and global disability scores at baseline but showed greater improvement than group 1 (n=47) who were younger with higher functioning at baseline. CONCLUSIONS This study assessed the impact of a novel cocreated, multi-technology, rehabilitation intervention on mobility and global function of people in the chronic phase of stroke recover. The results show overall improvement with the greatest improvement observed among participants with greater initial levels of disability. CLINICALTRIAL NCT06787768
Language: English
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4415250307