A case report of jejunal myeloid sarcoma presented with intestinal intussusception in a 19-year-old man: An uncommon presentation of a rare disease
Year: 2025
Type: article
Study design: Case Report
Abstract: Intussusception is a rare condition in adults, with an adult-to-pediatric incidence ratio of approximately 1:20. Unlike pediatric cases, adult intussusception is almost always secondary to an underlying pathological lesion. Myeloid sarcoma is an uncommon extramedullary manifestation of acute myeloid leukemia and represents a rare cause of gastrointestinal involvement. We report the case of a 19-year-old male who presented to the emergency department with acute abdominal pain and signs of intestinal obstruction. Abdominal computed tomography revealed jejunal intussusception. An exploratory laparotomy was performed, during which a necrotic lesion was identified on the jejunal wall, along with three additional lesions on the intestinal wall. A frozen section biopsy suggested differential diagnoses, including gastrointestinal stromal tumor (GIST) and intestinal lymphoma. The lesion causing the intussusception was resected with clear margins, while the remaining lesions were left in situ based on intraoperative pathology. Postoperative histopathological analysis confirmed the diagnosis of jejunal myeloid sarcoma. The patient was subsequently re-admitted for resection and re-anastomosis of the remaining lesions and was referred to the oncology department. Adult intussusception is often misdiagnosed due to its rarity and nonspecific presentation. In most cases, it is caused by an underlying lesion, which necessitates thorough intraoperative evaluation and appropriate surgical management. Myeloid sarcoma involving the gastrointestinal tract is exceptionally rare and may mimic other neoplastic conditions. This case highlights the importance of considering rare hematologic malignancies such as myeloid sarcoma in young adults presenting with intussusception. • Rare Adult Case: Intussusception is uncommon in adults and often linked to an underlying lesion—here, a 19-year-old male presented with abdominal pain and obstruction symptoms. • Initial Discovery: CT scan revealed intussusception; laparotomy exposed a necrotic jejunal lesion and three additional intestinal lesions. • Provisional Diagnoses: Frozen biopsy suggested possibilities of GIST or intestinal lymphoma, leading to selective resection. • Final Diagnosis: Post-op histopathology and immunohistochemistry confirmed jejunal myeloid sarcoma, a rare gastrointestinal malignancy. • Treatment Path: Remaining lesions were later removed; the patient was referred to oncology for probable chemotherapy, emphasizing the importance of accurate diagnosis and comprehensive surgical management.
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,090
OpenAlex ID: W4415258182