Work

Complete Remission of Recurrent Primary Cutaneous Anaplastic Large Cell Lymphoma Following Bexarotene Therapy: A Case Report

Year: 2025

Type: article

Abstract: Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a CD30-positive cutaneous T-cell lymphoma with a generally favorable prognosis. While radiotherapy is effective, recurrence is not uncommon. Herein, we report the case of an 87-year-old man with recurrent pcALCL who achieved complete remission after bexarotene treatment, despite resistance to radiotherapy and topical steroids. This case highlights bexarotene as a promising therapeutic option for refractory pcALCL. Our experience reinforces the potential of bexarotene as a viable treatment for pcALCL, particularly in recurrent or refractory cases where conventional therapies are contraindicated or ineffective.

Source: Cureus

DOI: 10.7759/cureus.94700

Authors: Natsumi Shimada, Natsuko Saito-Sasaki, Hitomi Fujimura, Hikaru Kawahara, Etsuko Okada, Yu Sawada

Institution: University of Occupational and Environmental Health Japan

Language: English

Topic: Cutaneous lymphoproliferative disorders research

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415265379