The Role of Incidental Magnetization Transfer in Divided Subtracted Inversion Recovery
Year: 2025
Type: article
Abstract: ABSTRACT Divided subtracted inversion recovery (dSIR) images show abnormal changes in the white matter of the brain in patients with mild traumatic brain injury (mTBI) due to an increase in the apparent T 1 compared to normal controls. The present study aims to understand the origin of the T 1 difference in terms of incidental magnetization transfer (MT). Results show that white matter in normal controls has dSIR signal (T 1 ), attributable to MT, while patients with mTBI exhibit little or no reduction. The study identifies a plausible mechanism for the dSIR signal differences. This may lead to more effective magnetic resonance imaging (MRI) methods for detecting mTBI and other conditions affecting the brain.
Source: NMR in Biomedicine
DOI: 10.1002/nbm.70165
Institutions: Mātai Medical Research Institute, Centre National de la Recherche Scientifique, Aix-Marseille Université, Centre de Résonance Magnétique Biologique et Médicale, University of Canterbury, New Zealand Brain Research Institute, University of Otago, University of Auckland, Pacific Radiology (New Zealand), University of California San Diego
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Hugh Green Foundation
OpenAlex ID: W4415267279