Work

Discovery of New N -H Aporphine Derivatives As Brain-Penetrant Gq-Biased 5-HT2C Receptor Agonists and Dual 5-HT2C/5-HT2A Receptor Agonists

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02115

Authors: Wangzhi Qin, Bingjie Zhang, Qi Wang, Guangqian Jiang, Jiaze Cui, Fan Chen, Ling Wang, Jiaojiao Chen, Sheng Tian, Xue-Chu Zhen, Wenqing Shui, Na Ye

Institutions: Soochow University, ShanghaiTech University

Language: English

Topic: Alkaloids: synthesis and pharmacology

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Priority Academic Program Development of Jiangsu Higher Education Institutions, ShanghaiTech University, Natural Science Research of Jiangsu Higher Education Institutions of China

Awards: G3551420921, G4398322572, G6717220243, G7337627874, G91941462

OpenAlex ID: W4415328539

FWCI:

Cites: 53

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