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Efficient Synthesis of Unsymmetrical 7,7′-Biindolizines

Year: 2025
Type: article
Abstract: Six new unsymmetrical 7,7′-biindolizines were synthesized through an efficient metal-free [2+2+1] cycloaddition of ethyl 3-benzoyl-7-(pyridin-4-yl)indolizine-1-carboxylate with two equivalents of dimethyl acetylenedicarboxylate in methanol. The transformation involves one C≡C triple bond cleavage and provides access to previously unexplored unsymmetrical functionalized 7,7′-biindolizines.
Source: Molbank
Language: English
Field: Chemistry
Open Access status: gold
Estimated APC paid: $603
OpenAlex ID: W4415369406
FWCI: 0.298
Cites: 31
Cited by: 1
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