Work

Diversity-Oriented Approaches toward the Synthesis of Cyclophanes

Year: 2025

Type: article

Abstract: Here, we describe synthetic approaches to a variety of cyclophanes involving transition-metal-catalyzed reactions such as the Suzuki-Miyaura cross-coupling, olefin metathesis, enyne metathesis, Glaser-Eglinton coupling, Yamamoto coupling, etc. On several occasions, alkylation, benzylation, Grignard reagents, and potassium thioacetate have been used for the construction of different cyclophanes like oxa-thiocyclophanes, heteroatom-containing cyclophanes, amino-acid-based cyclophanes, [6]-cycloparaphenylene, crownophanes, normuscopyridine, and macromolecules. Interestingly, these cyclophanes are useful in "host-guest" chemistry, molecular recognition, and supramolecular chemistry. This article can give useful recent information on advances related to the cyclophane area from our group along with others' work.

Source: ACS Omega

DOI: 10.1021/acsomega.9b00467

Authors: Sambasivarao Kotha, Milind Meshram

Institutions: Narsee Monjee Institute of Management Studies, Shri Vile Parle Kelavani Mandal, Savitribai Phule Pune University

Language: English

Topic: Synthesis and Properties of Aromatic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,935

Funders: Department of Science and Technology, Ministry of Science and Technology, India, Science and Engineering Research Board