Work

Successful Treatment of Paediatric Necrobiosis Lipoidica With Baricitinib

Year: 2025

Type: article

Abstract: ABSTRACT Necrobiosis lipoidica (NL) is a rare, chronic granulomatous condition that typically presents as sharply demarcated plaques with telangiectasia and atrophic centres. Paediatric cases are uncommon, and treatment options often fail to address refractory cases. We report a 13‐year‐old girl with progressive NL lesions that responded successfully to oral baricitinib, a Janus kinase inhibitor. Initial management with topical and systemic corticosteroids failed, but baricitinib led to significant lesion improvement within 6 months. This case highlights the potential of baricitinib in refractory paediatric NL and underscores the need for further research on its long‐term efficacy and safety.

Source: JEADV Clinical Practice

DOI: 10.1002/jvc2.70194

Authors: P. Simões Farinha, M. J. Paiva‐Lopes

Institutions: Unidade Local de Saúde de São José, Hospital de São José, Universidade Nova de Lisboa

Language: English

Topic: Skin Diseases and Diabetes

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,310