Year: 2025
Type: article
Study design: Clinical Trial
Abstract: . The aim of the study was to determine the effectiveness of the method of complex treatment of patients with venous DVT of the lower extremities in the modern concept of treatment of patients with DVT, the possibility of combining it with various methods of correction of CVI. Materials and methods of the study. The results of a comparative study of 71 patients are presented. In the main group of patients (n=35), surgical interventions were supplemented with layered dermatolipectomy followed by skin grafting with a split perforated autodermograft. Results and discussion. When using low-intensity laser radiation and fine spraying of Octenisept solution as a preoperative preparation, no complications or allergic reactions were recorded in both groups. After 1-2 sessions, all patients noted improvement in the form of a significant reduction in the intensity of pain, a decrease in the feeling of heaviness, burning and itching in the affected limb. After 5 sessions, 29 (82.9%) patients in group I and 32 (88.9%) patients in group II had complete pain relief. The long-term results of the treatment were monitored for up to 12 months. All patients of both groups were invited for a follow-up examination in 2, 6, and 12 months. No recurrence of TV was detected in any patient in group I. All patients in this group noted a positive effect of the treatment, satisfaction with the results of the surgical intervention and were transferred to C5 clinical class according to the SEAR. During follow-up examinations at the same time, 33 (91.7%) patients in group II also did not have a recurrence of TV. Reduction in the severity of CJD and a positive effect of the treatment were noted in 26 (72.2%) patients. The results obtained on the 5th day of treatment, in our opinion, are explained by the effectiveness of the combined effect of low-intensity laser radiation and fine spraying of the drug solution, which allows to achieve bactericidal, bacteriostatic, analgesic and sedative effects on the course of the phases of exudation and repair of the ulcer process. Fine-dispersed spraying of the drug makes it possible to exclude damage to the developing granulation tissue and to perform autodermoplasty in patients of both groups on 5.7±0.9 days from the beginning of hospitalization. Complete engraftment of the autodermograft was observed in 27 (77.1%) patients of group I and 7 (19.4%) patients of group II, which, in our opinion, is explained by the preoperative preparation of the trophic defect. Conclusions. Layered dermatolipectomy with autodermoplasty with a perforated flap in combination with surgical correction of venous hemodynamic disorders is an effective method of treating patients with clinical grade C6 chronic vein disease.
Source: Kharkiv Surgical School
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4415423743