Benzotriazole derivatives as alternate O-acetylserine sulfhydrylase substrates to impair cysteine biosynthesis in gram-negative bacteria
Year: 2025
Type: article
Abstract: , were demonstrated to have adjuvant effect in combination with selected approved antibiotics. While further optimization is required before their application, these molecules might find application as adjuvants of the antibiotic therapy and help to preserve existing drugs.
Source: iScience
Authors: Stefania Bova, Marialaura Pavone, Costanza Spadini, Nicolò Mezzasalma, Giacomo Quilici, Jole Maria Lucia D’Angelo, Francesca Malagutti, Omar De Bei, Chiara Spaggiari, Luca Ronda, Marco Pieroni, Stefano Bettati, Clotilde Silvia Cabassi, Barbara Campanini, Gabriele Costantino, Marialaura Marchetti, Giannamaria Annunziato
Institution: University of Parma
Language: English
Topic: Sulfur Compounds in Biology
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,240
Award: G8792988831
OpenAlex ID: W4415424722