Unanticipated papillary renal cell carcinoma in a complicated renal cyst: A case of radical nephrectomy following surgical complications
Year: 2025
Type: article
Study design: Case Report
Abstract: Cystic renal masses are often presumed benign, especially Bosniak I or IIF lesions. Rarely, papillary renal cell carcinoma (PRCC) can arise within these cysts, posing diagnostic and surgical challenges. We report a 40-year-old male with a right renal cyst under surveillance for three years as Bosniak IIF. Progressive growth led to laparoscopic cyst unroofing, but intraoperative findings of a solid mass and significant bleeding necessitated urgent radical nephrectomy. Histopathology confirmed pT2bN0Mx PRCC with solid and pseudopapillary features. This case underscores imaging limitations, the potential for malignancy in low-risk cysts, and the importance of vigilant monitoring, preoperative planning, and patient counseling. • Rare malignant potential: Papillary renal cell carcinoma can arise within cystic renal lesions initially classified as Bosniak IIF, even after long-term surveillance. • Diagnostic limitations: Imaging, including CT, may not reliably detect malignancy in apparently benign cysts, emphasizing the need for repeat assessment and careful preoperative planning. • Surgical challenges: Unexpected solid components and intraoperative bleeding may necessitate urgent radical nephrectomy, highlighting the importance of patient counseling. • Clinical implications: Vigilant follow-up, individualized management, and awareness of both oncologic and perioperative complications are essential to optimize outcomes.
Source: Urology Case Reports
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,160
OpenAlex ID: W4415426680