Parathyroidectomy and the use of ioPTH. A survey of the United Italian Society of Endocrine Surgery (SIUEC)
Year: 2025
Type: article
Study design: Observational Study
Abstract: Primary hyperparathyroidism (PHPT) is a frequent endocrine disorder, with surgery as the only curative option. Despite evolving guidelines, real-life management remains variable across centers. A national survey was conducted among members of the Italian Society of Endocrine Surgery (SIUEC) to evaluate current practices in PHPT surgery, including the use of minimally invasive approaches and intraoperative parathyroid hormone (ioPTH) monitoring. Eighty-eight endocrine surgeons participated. Minimally invasive parathyroidectomy was the preferred approach, especially among high-volume surgeons. ioPTH was used by 83% of respondents, although its necessity in cases with concordant imaging was debated. Cervical ultrasound and 99m Tc-sestamibi were routinely used for localization; choline PET/CT was employed selectively. Significant differences emerged between low- and high-volume surgeons in surgical technique, ioPTH timing, and use of neuromonitoring. The survey highlights heterogeneity in the management of PHPT in Italy, suggesting room for standardization and broader guideline adherence. Efforts are needed to promote uniform, evidence-based practices nationwide.
Source: Updates in Surgery
Authors: Paolo Del Rio, Salvatore Sorrenti, Giovanni Docimo, Gabriele Materazzi, Mario Testini, Pietro Giorgio Calò, Marco Raffaelli, Maurizio Iacobone, Carmela De Crea, Eleonora Lori, Elena Bonati, SIUEC PHPT Collaborative Group,, P. Alesina, M. L. Altana, G. Ansaldo, A. Antonino, A. Attard, E. Battistella, M. Belfiore, S. Beretta, C. Bergamo, M. Boniardi, M. Bononi, A. Borasi, A. Borrelli, M. Bossotti, A. Bove, E. Brugger, G.L. Canu, P. Capelli, L. Cestino, D. Chiari, M. Chicas Vasquez, F. Civitillo, F. D’Angelo, G. D’Onghia, V. D’Orazi, R. De Filippi, L. De Pasquale, A. Di Lascia, G. Dionigi, C. Dobrinja, G. Donatini, F. Feroci, A. Garbellini, A. Gatti, L. Giangreco, A. Giordano, G. Giraudo, G. Graceffa, A. Gurrado, N. Innaro, T. Loderer, G. Longo, R. Lucchini, V. Matteucci, F. Medas, R. Melcarne, A. Micalizzi, R. Minà, M. Minuto, G. Montecamozzo, M. Moretti, B. Mullineris, L. Oragano, M. Pacilli, N. Palestini, F. Palma, L. Palmieri, R. Panconesi, P. Papini, A. Pasculli, G. Pavone, F. Pedicini, M. Pelizzo, T. Perra, A. Pezzolla, D. Pironi, A. Porcu, F. Quaglino, E. Raggio, G. Ricci, L. Rosato, L. Rossi, G. Scerrino, D. Schiavone, L. Sessa, S. Spiezia, C. Talarico, N. Tartaglia, S. Tempera, I. Tiraboschi, A. Toniato, E. Traini, D. Tripodi, A. Tudisco, M. Veroux
Institutions: University of Parma, Sapienza University of Rome, University of Campania "Luigi Vanvitelli", University of Pisa, Azienda Ospedaliera Universitaria Pisana, University of Bari Aldo Moro, University of Cagliari, Università Cattolica del Sacro Cuore, Agostino Gemelli University Polyclinic, Istituti di Ricovero e Cura a Carattere Scientifico, University of Padua, Azienda Ospedale - Università Padova
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,790
Funders: Università degli Studi di Milano, Università degli Studi di Cagliari, Università degli Studi di Padova, Sapienza Università di Roma, Università degli Studi di Firenze, Università degli Studi di Genova, Università degli Studi di Parma, Università degli Studi di Palermo, Universita degli Studi di Bari Aldo Moro, Università degli Studi di Sassari, Università degli Studi di Torino, Università di Pisa, Universität Duisburg-Essen, Istituto Oncologico Veneto, Humanitas University, Università degli Studi di Perugia, Université de Poitiers
OpenAlex ID: W4415429105