Work

A Case Study of Unilateral Benign Lobular Inner Nuclear Layer Proliferations (BLIP) with Coexisting Congenital Hypertrophy of the Retinal Pigment Epithelium

Year: 2025

Type: article

Abstract: Retinal tumors emerging from the intrinsic cell types of the neurosensory retina are a rare entity. They are subdivided in benign retinal astrocytoma or -astrocytic hamartoma and malignant retinoblastoma, the latter of which requires immediate intervention. Recently, a fourth type of retinal tumor named Benign Lobular Inner Nuclear Layer Proliferations (BLIP) was described by Sanfilippo et al. based on its characteristic findings on optical coherence tomography (OCT) [ 1 ]. Only very few cases have been reported and its pathophysiology remains unclear to date. We report the clinical findings and multimodal imaging of a rare case of unilateral BLIP associated with a Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE) lesion.

Source: JFO Open Ophthalmology

DOI: 10.1016/j.jfop.2025.100183

Authors: Micheline Verhaegen, Vincent De Man, Ivo De Clerck, Julie Jacob

Institution: Universitair Ziekenhuis Leuven

Language: English

Topic: Ocular Oncology and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,680