Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction : Titanium dental implants are the most common type of dental implants. Although titanium and its alloys are considered biocompatible, there are concerns about the induction of metal allergy with dental implants. Aim : To evaluate the presence of titanium sensitization by patch testing in patients who intend to have titanium dental implants. Materials and methods : A retrospective study was performed in which data on sensitization to titanium collected from the Allergy Office at the Faculty of Dentistry in Plovdiv from January 2022 to April 2024 were analyzed. We analyzed data from 95 patients who had patch testing done before their dental implant surgery. Results : Thirty-eight (40.0%) patients exhibited positive patch test reactions to at least one metal. The most common allergen was nickel (32.6%). Titanium (IV) oxalate was the only one with a positive rate (7.4%) among titanium reagents. Almost one-half (42.9%) of the patients were monosensitized to titanium (IV) oxalate. No association between positive reaction to titanium (IV) oxalate and history of suspected metal allergy was identified ( p =0.064). Conclusions : The absence of positive reactions to other titanium reagents, as well as a correlation with a history of metal allergy and other allergies in patients who tested positive for titanium oxalate, makes determining the clinical relevance of the positive reactions difficult. Standardization in titanium allergy research is required to ensure the accuracy of the findings.
Source: Folia Medica
Authors: Iliyana Stoeva, Zlatina Tomova
Institution: Medical University Plovdiv
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415438443