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Abstract B036: A novel PDE10 inhibitor that blocks RAS and β-catenin signaling and enhances tumor immunogenicity with robust activity to inhibit tumor growth and metastasis

Year: 2025

Type: conference-abstract

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.targ-25-b036

Authors: Gary A. Piazza, Xi Chen, Dhana Sekhar Reddy. Bandi, Ganji Purnachandra. Nagaraju, Kristy L. Berry, Sindhu Ramesh, Khalda Fadlalla, Md Yeashin. Gazi, Upender Manne, Jeremy B. Foote, Adam B. Keeton, Yulia Y. Maxuitenko, Donald J. Buchsbaum, Gong Zhou, Bassel F. El-Rayes

Institutions: Auburn University, University of Alabama at Birmingham, Augusta University

Language: English

Topic: Phosphodiesterase function and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4415444694

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