Work

Abstract B119: FMC-376, a dual inhibitor of ON + OFF states of KRAS G12C, is active in sotorasib resistant PDX models

Year: 2025

Type: conference-abstract

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.targ-25-b119

Authors: Yan Wang, Alexey Sorokin, Preeti Kanikarla, Fengqin Gao, Zhensheng Liu, Shayna Simonstein, Karsten Krug, Scott Kopetz, Kevin R. Webster

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4415449772

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Cited by: 2

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