Shock index and early warning score in liver cancer rupture shock
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: BACKGROUND Primary liver cancer is a globally prevalent malignancy, with China accounting for approximately 55% of new cases, and is linked to hepatitis B, aflatoxin, and cirrhosis. Its rupture with hemorrhagic shock is a lethal complication with high mortality, and traditional triage struggles with timely risk stratification, necessitating better tools, such as the integrated shock index (SI)-early warning score (EWS). AIM To study and analyze the combined effect of the SI and EWS in primary liver cancer patients with ruptured hemorrhage and shock. METHODS In total, 118 patients who visited the Emergency Department of Nantong Third People's Hospital from January 2023 to December 2024 were selected and randomly divided into a control group (59 patients who received routine emergency treatment) and an observation group (59 patients who received condition assessment and intervention by combining the SI and EWS based on routine emergency treatment). The clinical treatment outcomes, respiratory function indicators, serological indicators, complications, and satisfaction with emergency intervention before and after the emergency intervention were compared between the two groups. RESULTS The emergency, triage, waiting, and hemostasis times, as well as hospital stay were shorter in the observation group than in the control group (P < 0.05). After 48 hours of emergency intervention, blood oxygen saturation and partial pressure of oxygen in the observation group were higher than those in the control group (P < 0.05). Seven days after emergency intervention, the hemoglobin, prealbumin, and albumin levels were higher in the observation group than in the control group (P < 0.05). The complication rate in the observation group was 3.39%, lower than that in the control group (13.56%; P < 0.05). Satisfaction with emergency intervention in the observation group was 94.92%, higher than 83.05% in the control group (P < 0.05). CONCLUSION The combined application of the SI and EWS in patients with primary liver cancer rupture, hemorrhage, and shock can significantly shorten emergency treatment time, improve respiratory function and serological indicators, reduce the incidence of complications, and enhance patient satisfaction with emergency interventions, with higher clinical treatment efficiency and quality. Therefore, it is worthy of promotion and application.
Authors: Ji-Fen Ma, Li Jin, Ling Sha, Hong-Fang Li, Xiang-Yun Qian, Hai-Yan Wang
Institutions: Nantong University, Affiliated Hospital of Nantong University
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415465257