Work

Single-cell RNA profiling of blood CD4+ T cells identifies distinct helper and dysfunctional regulatory clusters in children with SLE

Year: 2025

Type: article

Study design: Observational Study

Source: Nature Immunology

DOI: 10.1038/s41590-025-02297-2

Authors: Preetha Balasubramanian, Uthra Balaji, Marina Silva Santos, Jeanine Baisch, Cynthia Smitherman, Lynnette Walters, Paola Sparagana, Lorien Nassi, Katie Stewart, Julie Fuller, Terry Means, Virginia Savova, Jacques F. Banchereau, Tracey Wright, Virginia Pascual, Jinghua Gu, Simone Caielli

Institutions: Weill Cornell Medicine, Texas Scottish Rite Hospital for Children, Children's Medical Center, The University of Texas Southwestern Medical Center, AstraZeneca (United States)

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases

Awards: G1472208999, G1650651783, Center for Lupus Research, Immune Cells and Secretory Pathways Leading to Human Systemic Autoimmunity

OpenAlex ID: W4415468890

FWCI: 10.84

Cites: 60

Cited by: 15

Related to: 10