Toxic epidermal necrolysis as a rare complication of pembrolizumab immunotherapy in the treatment of squamous cell lung cancer
Year: 2025
Type: article
Study design: Case Report
Abstract: Toxic epidermal necrolysis (TEN, Lyell's syndrome) and Stevens-Johnson syndrome (SJS) are a continuum of severe, life-threatening drug reactions involving separation of the epidermis, erythematous or purpuric lesions, skin blisters, and mucosal erosions, resembling severe burns.Above mentioned syndromes are differentiated based on the proportion of body surface affected by the lesions, i.e.SJS affects <10% of the body surface, TEN >30%, and involvement of 10-30% of body surface is defined as SJS/TEN overlap [1].A 65-year-old male patient with generalized squamous cell carcinoma of the left lung was admitted to the Pulmonology, Allergology, and Internal Medicine Department due to pneumonia and swallowing disorders.Physical examination revealed extensive erythematous
DOI: 10.20452/pamw.17145
Institutions: Szpital Uniwersytecki w Krakowie, Jagiellonian University
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415477810