Work

Dual Inhibitors of KRASG12D and HSP90 Are Effective against KRASG12D Inhibitor Resistance

Year: 2025

Type: article

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.mct-24-1173

Authors: Ines Pulido, Laura C. Gunder, Chenghao Ying, Yaya Wang, Yan Dai, Zimo Yang, Alireza Rahnama, Jinhua Li, Yuetong Sun, Chuhe Liu, Haoxin Zhou, Guoqiang Wang, Kevin P. Foley, Khaled Abdelhady, Malek G. Massad, Thomas L. Prince, Ian Papautsky, Weiwen Ying, Takeshi Shimamura

Institution: University of Illinois Chicago

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: U.S. Department of Defense, National Institutes of Health, National Cancer Institute

Awards: G15865141, Investigation of CXCR7 signaling in EGFR TKI resistant NSCLC, EXPLORING METABOLIC VULNERABILITY OF KRAS G12C INHIBITOR RESISTANCE, THE USE OF MICROFLUIDIC LUNG CANCER ON A CHIP IN INVESTIGATING NOVEL DRUG RESISTANCE, IMPROVE THE EFFICACY OF LUNG CANCER THERAPY BY TARGETING THE EDN1 AXIS, G5878202925

OpenAlex ID: W4415478432

FWCI: 0.252

Cites: 31

Cited by: 1

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