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Rational Engineering of a Pseudaminic Acid Synthase Enzyme Enables Access to a 3‐Fluoro Sugar with Motility Inhibition in Bacterial Pathogens

Year: 2025

Type: article

Source: Angewandte Chemie

DOI: 10.1002/ange.202515851

Authors: James M. Jeffries, Abigail J. Walklett, Natasha E. Hatton, Bartosz Kowalski, Tessa Keenan, Lickson Munjoma, Richard Haigh, Christopher D. Bayliss, Gavin H. Thomas, Martin A. Fascione

Institutions: University of York, University of Leicester

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: closed

Funders: Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council

Awards: Technologies for the Future, Core Capability - University of York, Midlands Integrative Biosciences Training Partnership (MIBTP)

OpenAlex ID: W4415494456

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Cites: 37

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