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Long-acting Cabotegravir/Rilpivirine for Treatment of HIV During Pregnancy: A Case Series

Year: 2025
Type: article
Study design: Case Report
Abstract: We present pharmacokinetic data on long-acting cabotegravir/rilpivirine (LA CAB/RPV) from two patients during their second and third trimesters. Monthly LA CAB/RPV dosing maintained concentrations above the proposed efficacy thresholds while bimonthly dosing resulted in subtherapeutic RPV concentrations. This highlights the potential of monthly LA CAB/RPV dosing in pregnancy.
DOI: 10.1093/ofid/ofaf649
Authors: Shawnalyn W Sunagawa, Carly Cloud Floyd, Sara H Bares, Anthony T Podany, Kimberly K Scarsi, Timothy Mykris, Lee Winchester, Jennifer O’Neill, Maureen Kubat, Christine Tran, Jennifer M Davis, Jeremy W Snyder, Joshua P Havens
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $4,053
OpenAlex ID: W4415502953
FWCI: 4.96
Cites: 13
Cited by: 7
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