Work

Compromised pressure-generating capacity of diaphragmatic muscle and its interaction with the lower rib cage at high lung volume during airway occlusion

Year: 2025

Type: article

Abstract: Data from the current study support the hypothesis that the pressure-generating capacity of the diaphragm at high lung volume is compromised primarily due to a mechanism that involves a combined mechanical effect of hyperinflation and substantial muscle contraction rather than a significant loss of its muscle fiber curvature.

Source: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

DOI: 10.1152/ajpregu.00080.2025

Authors: Aladin M. Boriek, Noralis Rodriguez-Santiago, Sanghyun Kim, Aubri Ford, Shari Wynd, Rolf D. Hubmayr

Institutions: Baylor College of Medicine, Texas Chiropractic College, Mayo Clinic

Language: English

Topic: Respiratory Support and Mechanisms

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: United States-Israel Binational Science Foundation, National Heart, Lung, and Blood Institute